|firma:||Research Institute of Creative Education|
|tytuł:||Cordycepin from fermentation liquid of Cordyceps Militaris protects against liver injuries in mice model|
|autorzy:||1. NGUYEN BA VIET CUONG 2. NGUYEN SINH NHAT ANH 3. NGUYEN DUC TRUONG PHUC 4. HOANG LE CHI 5. PHAM MINH PHUONG|
|opis:||Cordycepin from the fungus Cordyceps militaris exhibits various bio-
activities. It were shown to possess anti-cancer, anti-inflammatory and anti-
bacterial activities, and immune regulation. However, up to date, there has not
been any deep study on the role of Cordycepin from fermentation liquid of
Cordyceps militaris interacts to cause a hepatitis effect remains unknown. In this
study, a maximum production of Cordycepin was 113 µg/mL. Furthermore, oral
treatment with Cordycepin from fermentation liquid of Cordyceps militaris
exhibited a significant decrease in the levels of GOT, GPT, ALP, Bilirubin.
Histophathological examination demonstrated lower liver damage in Cordycepin-
treated mice as compared to CCl 4 -treated mice.
Collectively, these data indicated that hepatoprotective effects of Cordycepin
from fermentation liquid of Cordyceps militaris on CCl 4 -induced hepatic damage
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